Wednesday, January 27th, 2021

Scientists Create Baby Mice Without Using Fertilized Eggs

Published on September 20, 2016 by   ·   No Comments



Scientists in the UK have found a method of creating offspring without using female eggs.

In an experiment at Bath University scientists successfully created healthy baby mice using sperm that was injected directly into modified, inactive mouse embryos rather than from a fertilized egg cells.


International Business Times reports:

This is the first time offspring have been born without egg cells, suggesting the process of fertilisation is more complicated than we once thought.

It is important to be clear – an egg was required for the mice to be born. In their study published in Nature Communications, scientists started with an egg and created an artificial signal to make it develop into an embryo. Normally, these embryos – parthenogenotes – die after a few days because they need sperm to continue the developmental process.

However, researchers were able to inject sperm into the parthenogenotes to allow fertilisation. Moreover, the fertilised embryos resulted in healthy mice being born in 24% of the experiments.

Tony Parry, a molecular embryologist and senior author of the paper, said: “This is first time that full term development has been achieved by injecting sperm into embryos. It had been thought that only an egg cell was capable of reprogramming sperm to allow embryonic development to take place.”

Read More HERE

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