
A vaccine being developed in Chile will give anyone who drinks alcohol and immediate hangover
A new vaccine will give anyone who drinks even a small amount of alcohol an immediate and very heavy hangover.
Scientists from the University of Chile have spent a year designing the drug in a bid to tackle the growing problem of alcoholism in the country.
The vaccine, which would be effective for between six months and a year, works by sending a biochemical message to the liver telling it not to express genes that metabolise alcohol.
Normally, the liver turns alcohol into the hangover-causing compound called acetaldehyde which is then broken down by a metabolising enzyme.
If someone who’s been vaccinated tries to drink alcohol, they will immediately experience severe nausea, accelerated heartbeat, and general discomfort.
Once the vaccine has been administered it cannot be reversed.
A preclinical trial using mice to determine the correct dosing is due to begin next month with researchers hoping to begin tests on human subjects in November.